I am terrible in the morning and better at night as well.
Before I tested positive for PPTU, I thought liver flushing was helping. Looking back, it was most likely the epsom salts (laxative) that were cleaning me out and that was what was giving me relief. I'd always have a couple days of improved health and mental clarity after every flush.
I worked with an endocrinologist and they ran a battery of tests on me. The endocrinologist was never able to pinpoint anything. My numbers were sometimes erratic. Not Addison's, not Cushing's but the numbers would sometimes point in the direction of both, depending on what they were testing and when. But the numbers were never drastically in one range or the other.
I remember one of the tests was urine metanephrines but nothing conclusive ever came up.
"Since these tests are affected by drugs, foods, and stresses, false positive
tests may occur. For this reason, metanephrines testing is not
recommended as a screen for the general public. Doctors will frequently
investigate a positive result by evaluating a person's stress, diet,
and medications, work to alter or minimize these influences, and then
repeat the test to confirm the original findings."
Based on how I've felt when treatments have temporarily worked, I know now that all of these symptoms, at least all of the symptoms that I experience, are tied directly to this parasite. I used to think I had thyroid issues or adrenal issues or any number of things, but it's clear to me now that this is not the case.