I tried LDN. I went on it first starting at 1.5mg for over a week or so day, then added the second pill to bring the dosage up to 3mg. I had a Rx from my functional medicine doctor and had a compounding pharmacy make the capsules. I consistently took it every night between 10:30 and 11:00 pm. For the first week I felt terrible, alot of fatigue, no change in d, muscle fatigue...alot like c.diff was coming back. But I stuck with it, and those symptoms died down. I stuck with it because there is a doctor at Hershey Medical that has had great success with reversing Chron's disease and my sister-in-law knows someone at the hospital she works at who was a patient out at Hershey and she said it reversed her Chrons's. So I figured it could help the body fight what ever bacteria caused her disease, why couldn't it help my body figure out a way to fight a parasite.
I stayed on it for close to 3 months faithfully and after the initial worsening of symptoms, I had some minor improvements. My bowels were ever so slightly formed, my fatigue was a little better, and the biggest thing was my gut inflammation really seemed to be reduced. Less swelling across and less pain on my right side.
I had night sweats all the time....but I get these several times a week anyway with blasto. I could sleep no problem (it is such a low dose) but I did have wicked dreams. Very scary real dreams about family members.
It alone for me is not the answer. I stopped after close to 3 months for a few reasons. The first is it was costing $95 a month and that just seemed like alot for something with not such great results. All these out of pocket expense cost to much and I have to pick and choose. And second I was still taking herbs to try and keep the blasto at bay and ended up with active c.diff again and stopped everything but getting on vanco to get that bacteria infection under control. I am still keeping it on the possible list and actually filled my last Rx and have it ready to go.
I plan on using it along with with some sort of biofilm blaster, and maybe vitamin c, when I try and go on another round of antibiotics for blasto.
Let us know how you do on it and what else you are taking at the same time. Maybe the key is the combo of things.