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linenup

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May 31 15 3:15 AM

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A very well written article outlying the problems with biofilm environments. The authors show that organisms that were not resistant to antibiotics, can now have that property when in the biofilm environment. 

Antibiotic resistance of bacteria in biofilms
Philip S Stewart, J William Costerton
Review
Bacteria that adhere to implanted medical devices or damaged tissue can encase themselves in a hydrated matrix of
polysaccharide and protein, and form a slimy layer known as a biofilm. Antibiotic resistance of bacteria in the biofilm
mode of growth contributes to the chronicity of infections such as those associated with implanted medical devices.
The mechanisms of resistance in biofilms are different from the now familiar plasmids, transposons, and mutations
that confer innate resistance to individual bacterial cells. In biofilms, resistance seems to depend on multicellular
strategies. We summarise the features of biofilm infections, review emerging mechanisms of resistance, and discuss
potential therapies.



http://instructional1.calstatela.edu/tsalmas/Micr%20331/Stewart%20and%20Costerton%202001.pdf

 

Last Edited By: linenup May 31 15 3:38 AM. Edited 1 time

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May 31 15 3:44 AM

There appears to be a number of remedies for biofilm environments IMO the best is lactoferrin or lactoferrin with xylitol of which xylitol causes some problems for some people. Lactoferrin is naturally produced by the body and is in fair amounts in colostrum and mother's milk. Its job is the stop biofilm environments which part of that is to inhibit iron or sequester iron in the body since it is used in biofilm creation. As a side note, you will see people who become sick have pale skin. I think that is due to iron being sequestered.

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