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I went to Kansas hunting a couple of weeks ago and carried 45 or 50 lbs of gear up and down those Kansas hills for a week. I had no popping joints, no sleep issues, and no signs of having any type of protozoal infection. The exercise increased blood flow enough to clear almost all of the protozoans IMO. I did eat restaurant food the entire week which is very different from my typical diet. Once I got home, it took 3 to 4 days of not exercising for the mucus/biofilm to start reforming around my epiglottis. A couple days later, the joint popping came back as did the sleep problems. I was sleeping 3 or 4 hours a night. My stools changed to a lighter color and they became more of a chalky texture. I read a lighter colored stool could mean I had decreased biliary drainage so I took an All in One multivitamin and a Pancreatic/VDR FOK relief capsule from Yasko. I slept 5 to 6 hours the next two nights which is closer to normal for me now. IMO, the joint popping and sleep issues are from an increase in protozoan growth and their removal by my immune system. So many were being killed that it overloaded my system and I couldn't get rid of the by products fast enough. It is my opinion that for any treatment protocol to work, exercise will have to be major part of the protocol.