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linenup

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#21 [url]

May 22 14 11:28 PM

Which website or program is best to import the raw data from 23andMe? Thanks.

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#23 [url]

May 24 14 4:04 AM

ebrooker wrote:

FL1953 wrote:
I just received my 23andme test results and I'm devastated. I feel like the parasite has caused some of these mutations as I was doing very well before I contracted the disease. My parasite causes an increase in Polyamine production and my immune response keeps my pathways right at the point of being overloaded. Polyamines directly initiate transcription!  In case you missed it, polyamines directly initiate transcription. 

Here are my mutations:

MTHFR C677T +/-
MTHFR A1298C +/-
VDR Bsm +/-
BHMT-02 +/-
BHMT-08 +/-
CBS C699T +/-

And homozygous

VDRTaq +/+
MAO-A R297R +/+
MTRR A66G +/+
MTRR A664A +/+

I now have doubts as to whether my protocol will ever be effective.  There are just so many mutations and obstructions to overcome, I'm not sure it's possible.  I'll digest this info for a few days, regroup, and go from there.  This was a pretty big blow.

What do these results mean FL?

It means what I thought would work is now going to be difficult.  I have a couple mutations in bad spots that explain some of my symptoms.  I will go on record as saying I do not believe I had all of these mutations until after I was bitten.  I believe the parasite directly interferes with DNA transcription and allows single nucleotide point mutations to occur.  Yasko doesn't think so, but she didn't have cherry angiomas come up on here after she was bitten.  I did.  These cherry angiomas have to be a way the body eliminates toxins or free radicals.  Getting toxins out of the body is paramount, like losing hair so that we can shed excess metals. 

In order for my theory to work, I have to keep my methyltransferase level high and the BHMT mutations with the others make this difficult to do.  Maybe that is how the parasite gets it's foothold, it causes a couple of mutations that keep you from ingesting substances that kill it.  When I drink green tea or coconut milk, I immediately sleep better and feel better.  It could be from something simple like they help my adrenal fatigue, but I can't forget the article showing catechins inhibiting parasite growth.  After a couple of days of green tea and coconut milk, I'm a basket case.  My pathway crashes along with all my neurotransmitters.  A lot of supplements came in yesterday and as soon as I get some baseline tests, I'll start supplementing.  If I can get the pathways running pretty good, I'll throw in the catechins and napthoquinones for the parasites.  It may be something I have to pulse. 

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linenup

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#25 [url]

May 25 14 2:53 AM

How much is really known about these outcomes (?), so if the gene is impaired then I would think that it just needs some support.  Besides Dr. Yasko how much is really known? 

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#26 [url]

May 25 14 8:08 AM

linenup wrote:
How much is really known about these outcomes (?), so if the gene is impaired then I would think that it just needs some support.  Besides Dr. Yasko how much is really known? 

There are others working in the field, Yasko just has a lot of experience dealing with individuals.  You would think you would have serious issues with Vitamin D with that profile and the AHCY can make you an over methylator.  Your methylation pathway will be working at 70% from the 1298 and the others will effect it as well.  Her methylation plan can be downloaded and it will explain each mutation.  I don't like some of her supplements, but that is just me.  I ordered the All In One multivitamin because it has some really good things in it.  All of us would benefit from that.  I ordered a few more here and there but nothing like she reccommends. 

Yasko says the CBS mutations are upregulators, but others in the field disagree.  They say the 699 is an upregulatory gene and that the other CBS enzymes are not.  Maybe she needs to clarify her position more, but I'm siding with the others on this one.  At least your 699 is normal. 

Knowing this will help, but we have to rid ourselves of our pathogens if we want to get well.  Support the pathway and keep searching for ways to get cured.

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#29 [url]

May 28 14 3:37 AM

linenup wrote:
http://vitals.nbcnews.com/_news/2012/11/28/15518402-study-shows-surge-of-bad-disease-genes-in-europeans?lite

An article about genetic mutations that are occurring more rapidly within European descent. The article does not take into account other causative factors for disease such as environmental toxins, poor nutrient status etc.

Interesting, thanks.  When those protozoans are attached to ornitine decarboxylase inside the nucleus and DNA transcription occurs, they have got to interfere with translation.  They physically get in the way.  DNA is huge and uncoiling it takes up all the room inside the nucleus.  I didn't have cherry angiomas until I got this disease.  They come (IMO) from a breakdwon of my metabolic pathways (CBS) due to single nucleotide mutations which slow the pathway.  The pathway becomes overloaded due to metal accumulation and toxins and the body tries to get those toxins as far away from the organs as it can. 

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#30 [url]

Jun 11 14 1:20 PM

Got some test results back that were interesting. Asparate, Phosphoethanolamine, Cystathionine, and pretty much all of my polyvalent cations were low. Beta - alanine and Anserine were high. I've got to figure out what this all means, but I did see something interesting. Ethanolamines are used to make sphingomyelins. Sphingomyelins are used to make the cell membranes of RBC's. The chemical structure of the long side chain for each of these products is identical to the side chain containing LPS on a piroplasm. It would be easy for it to be incorporated into the cell membrane of a RBC. Now for the kicker, the side chain of coconut is identical to these side chains. I herx just about every time eat coconut cream. IMO, coconut kills it or at least displaces it and allows my immune response to get it. It probably only kills the gametocytes and merozoites, but at least it does something. I'll read more when I have time. I'm sleeping around 7 hours a night now, so the methylation supplements are helping.

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linenup

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#32 [url]

Jun 14 14 12:31 AM

Someone sent this video to me. I just skipped through a lot of parts but ran across the discussion about the Fry Labs new protozoa FL 1953. I do not know the details of her situation whether it was truly Lyme that was causing the problems and what the outcome of the treatments.

I am not convinced that the Lyme diagnosis that most practitioners make are strictly caused by the bacteria associated with Lyme as many other pathogens can mimic Lyme. My situation closely resembles Lyme but is caused by the parasite. Comments are welcome.

Start at 56:00 to see about the Fry Labs report.  (for some reason the video starts at 51:00 and not 56:00)

?t=56m40s

Last Edited By: linenup Jun 14 14 12:47 AM. Edited 4 times.

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#34 [url]

Jun 16 14 3:42 AM

Thanks Troyza, good stuff.  Lineup, that was one of the first videos I watched several years ago.

Here is my deal, I'm normal.  If I walk up and talk to any one of you, I seem just as normal as can be.  Nothing out of the ordinary except for one thing, I was performing at an extremely high level when I got sick.  I was doing things that other people could not do and this parasite rendered me "normal."  When I say normal, both phyically and intellectually.  I'm not close to what I was before this infection and I'd like to get back to that.  An untrained eye would just say "I'm getting older" but I know better.  That's never an excuse.

 

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#35 [url]

Jul 4 14 2:55 AM

I just finished my forth day of my protocol and so far so good. My immune system took a hit but I've been able to get through it with minimal issues. Perhaps the methylation pathway supplementation is working? I'm planning a couple months of treatment and get progressively more aggressive as I get later in the protocol. My problem as has always been getting 100% parasite elimination. I can kill a lot of them, but haven't been able to get to 100%.

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#37 [url]

Jul 8 14 2:48 AM

linenup wrote:
This is using the original protocol?
 

Yes, but going at it slower this time.  I'm supporting my methlation pathway this time and seem to be making progress.  I'm a week in now and the only issues I've had are that I'm sleeping a lot less and I had a mouth ulcer.  I never have mouth ulcers so something is happening.  I did have a ton of cherry angiomas come up but that could have been since I ate some pizza.  It was my daughter's birthday and when I start feeling better, I eat crap. 

I remember that the last place my body popped and creaked when on Mepron was my neck.  Low and behold, my neck starting popping 3 days into it.  Something is going on, and libido is up.  That's usually a good indicator that I'm progressing.  This week will be interesting as I start to introduce the juglone/coconut oil mix into my diet. 

I also started exercising to increase the blood flow to my hard to access regions.  I'm popping all over now and that was limited to only my feet before. 

I'm going to be introducing some planned post exercise insulin spikes into my diet later this week or next week.  I'm trying to increase the intracellular concentrations of epigallocatechins. 

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#38 [url]

Jul 8 14 11:33 AM

I'm getting my but kicked today. The juglone/coconut oil with green tea is making me feel like crap. I may have to go to every other day. I hate this feeling but it's necessary.

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#40 [url]

Jul 11 14 3:36 AM

linenup wrote:
Thanks for replying - I have read some issues with the toxicity of black walnut, do you think this is one causing problems?  

Yes.  There are so many receptor targets for that molecule in a biological system that the intended receptor on the pathogen is difficult to reach.  My intent is to get to the appropriate level needed to suppress parasite growth while not inducing toxity.  Trial and error, time, and luck will be needed.  I'll do this for a month or so before adding additonal parasiticidal agents. 

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